2-hydroxy -5-pyridyl broMide
2-Hydroxy-5-bromopyridine
CAS: 13466-38-1
Molecular Formula: C5H4BrNO
2-hydroxy -5-pyridyl broMide - Names and Identifiers
| Name | 2-Hydroxy-5-bromopyridine |
| Synonyms | 5-bromopyridin-2-ol 5-Bromo-2-pyridinol 5-Bromo-2(1H)-pyridone 5-bromopyridin-2(1H)-one 5-BroMo-1H-pyridin-2-one 2-Hydroxy-5-bromopyridine 5-Bromo-2-hydroxypyridine 5-bromo-2-hydroxy pyridine 2-hydroxy -5-pyridyl broMide 5-Bromopyridin-2-ol, 5-Bromopyridin-2(1H)-one 5-Bromo-2-pyridinol5-Bromo-2(1H)-pyridinone5-Bromo-2-pyridone |
| CAS | 13466-38-1 |
| EINECS | 629-311-5 |
| InChI | InChI=1/C5H4BrNO/c6-4-1-2-5(8)7-3-4/h1-3H,(H,7,8) |
| InChIKey | NDMZZQRNZFWMEZ-UHFFFAOYSA-N |
2-hydroxy -5-pyridyl broMide - Physico-chemical Properties
| Molecular Formula | C5H4BrNO |
| Molar Mass | 174 |
| Density | 1.776±0.06 g/cm3(Predicted) |
| Melting Point | 180-183°C(lit.) |
| Boling Point | 305.9±42.0 °C(Predicted) |
| Flash Point | 138.8°C |
| Vapor Presure | 0.000796mmHg at 25°C |
| Appearance | Crystalline Powder |
| Color | Off-white to yellow-brown |
| BRN | 108751 |
| pKa | 9.96±0.10(Predicted) |
| Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
| Refractive Index | 1.6 |
2-hydroxy -5-pyridyl broMide - Risk and Safety
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R36 - Irritating to the eyes R22 - Harmful if swallowed |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37/39 - Wear suitable gloves and eye/face protection S36 - Wear suitable protective clothing. |
| WGK Germany | 3 |
| HS Code | 29339900 |
| Hazard Class | IRRITANT |
2-hydroxy -5-pyridyl broMide - Reference Information
| introduction | 2-hydroxy-5-bromopyridine is off-white to yellow-brown crystalline powder, which is an important pesticide and pharmaceutical intermediate. In the traditional process, pyridine is used as the starting material, and 5-bromo-2-chloropyridine is prepared by diazotization reaction and Sandmeier reaction, and then high-boiling alcohol is used as a solvent to react with potassium alcohol. Hydrolysis to obtain the compound. |
| properties | 2-hydroxy -5-bromopyridine is gray-white to yellow-brown crystalline powder, density: 1.776g/cm3, boiling point: 305.9°C at 760 mmHg, melting point: 180-183 c (lit.). |
| Synthesis method | Using pyridine as the starting material, 5-bromo-2-chloropyridine is prepared by halogenation reaction, and then high boiling point alcohol is used as the solvent After the reaction with potassium alcohol, the target compound 2-hydroxy-5-bromopyridine is hydrolyzed to obtain the target compound 2-hydroxy-5-bromopyridine. The synthesis reaction formula is as follows: |
Last Update：2024-04-09 21:11:58
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View History
2-hydroxy -5-pyridyl broMide
2-QuinoL
C.I. 77820
15518-76-0
INDOLE-4-METHANOL
疟涤平
halofantrine hydrochloride
氮化铬粉
3032-11-9
2-QuinoL
C.I. 77820
15518-76-0
INDOLE-4-METHANOL
疟涤平
halofantrine hydrochloride
氮化铬粉
3032-11-9